Troponin I antibody (Cardiac) (10R-T123a)

Mouse monoclonal Troponin I antibody (Cardiac)

Synonyms Monoclonal Troponin I antibody (Cardiac), Anti-Troponin I antibody (Cardiac)
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA, IHC, IP, WB
Immunogen Troponin I antibody (cardiac) was raised in mouse using amino acid residues 18-28 of cTnI as the immunogen.

Specifications

Host Mouse
Clone M18
Isotype IgG1
Residues Epitope specificity: 18 ? 28
Method of Purification Troponin I antibody (Cardiac) was purified by chromatography on protein A Sepharose.
Form & Buffer Protein A purified IgG supplied in PBS, pH 7.5, 0.1 % NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. cTnI molecule contains two serines in the 22 and 23 positions. Both amino acid residues can be phosphorylated in vivo by protein kinase A, so four forms of protein ? one dephospho, two monophospho and one bisphospho ? can coexist in the cell.

References
Add a Paper

Sungho Koa, Bumjun Kimb, Seong-Sik Job, Se Young Ohc, Je-Kyun Park

Electrochemical detection of cardiac troponin I using a microchip with the surface-functionalized poly(dimethylsiloxane) channel

Biosensors and Bioelectronics

Volume: 23 Issue: 1 Page: 51-59 DOI: 10.1016/j.bios.2007.03.013

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Availability: In stock

Price: $484.00
Size: 1 mg
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