Troponin I ELISA kit (55R-1876)
ELISA kit for the detection of Troponin I in the research laboratory
|Assay Information||Sensitivity: < 0.38 ng/ml|
|Biological Significance||Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.|
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