Troponin I protein (Cardiac) (Rabbit) (30-1010)

Purified native Rabbit Troponin I protein (Cardiac)

Synonyms Troponin I protein, cTnl protein, Cardiac-specific troponin I protein, TnI protein
Species Rabbit
Protein Type Native

Specifications

Source Cardiac Tissue
Purity > 90% pure
Method of Purification Troponin I protein was purified by Tn-C affinity chromatography.
Molecular Weight 22-24 kDa
Form & Buffer Supplied in 8M Urea, 50 mM Tris.HCl, 5 mM beta-mercaptoethanol, 2 mM EDTA, 0.5 mM CaCl2, pH 7.4
Concentration 0.25 - 2.0 mg/mL

Storage & Safety

Storage Store at -25 deg C or below. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

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Availability: In stock

Price: $495.00
Size: 100 ug
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