Troponin I protein (Skeletal Muscle) (Rabbit) (30-1015)

Purified native Rabbit Troponin I protein (Skeletal Muscle)

Synonyms TnI protein, cTnl protein, Troponin I protein, Cardiac-specific troponin I protein
Species Rabbit
Protein Type Native

Specifications

Source Skeletal Muscle
Purity > 95% pure
Method of Purification Troponin I protein was purified by Tn-C affinity chromatography.
Molecular Weight 22 kDa
Form & Buffer Supplied in 8M Urea, 100 mM NaCl, 50 mM Tris.HCl, 1 mM EDTA, 15 mM beta-mercaptoethanol, pH 7.4
Concentration 0.25 - 2.0 mg/mL

Storage & Safety

Storage Store at -25 deg C or below. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

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Availability: In stock

Price: $475.00
Size: 100 ug
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