TTC11 protein (His tag) (80R-1326)

Purified recombinant Human TTC11 protein

Synonyms FIS1 protein, FIS 1 protein, hFis1 protein, TTC11, TTC-11, CGI135 protein, TTC 11, homolog of protein, Fission 1 (mitochondrial outer membrane) homolog (S protein, Tetratricopeptide repeat protein 11 protein, cerevisiae) protein, Mitochondrial fission 1 protein protein, TPR repeat protein 11 protein, cerevisiae protein, TTC 11., Fis1 homolog protein, Fission 1 (mitochondrial outer membrane) homolog protein, CGI 135 protein, S protein, Fission 1 (mitochondrial outer membrane) homolog (yeast) Fission 1 homolog protein, H NH0132A01.6 protein, hFis 1 protein, TTC-11 protein, FIS1 protein, Tetratricopeptide repeat domain 11 2010003O14Rik protein, TTC 11 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 1-122 amino acids: MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
Expression System E.coli
Purity > 95% pure
Molecular Weight 16.3 kDa(142aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl Buffer, pH 8.0, containing 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission. Recombinant human TTC11, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

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Availability: In stock

Price: $220.00
Size: 100 ug
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