TUG antibody (10R-1832)
Mouse monoclonal TUG antibody
|Synonyms||Monoclonal TUG antibody, Anti-TUG antibody|
|Immunogen||TUG antibody was raised in Mouse using a purified recombinant fragment of TUG expressed in E. coli as the immunogen.|
Western Blot analysis using TUG antibody (10R-1832)
Western Blot showing TUG antibody used against NIH/3T3 cell lysate.
|Form & Buffer||Purified antibody supplied in PBS containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.|
Sorry, but there are no references currently for this product.
You need to be logged in to write a review. Please login here
Sorry there are currently no reviews for this product