TXNL4B protein (His tag) (80R-1846)
Purified recombinant TXNL4B protein
|Synonyms||Dim2 protein, TXNLB 4, TXNLB-4, TXNL4B, thioredoxin-like 4B protein, TXNLB 4 protein, TXNLB-4 protein, DLP protein, FLJ20511 protein|
Coomassie Blue stained SDS-PAGE of TXNL4B protein (His tag) (80R-1846)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-149 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSFL LPKLTSKKEV DQAIKSTAEK VLVLRFGRDE DPVCLQLDDI LSKTSSDLSK MAAIYLVDVD QTAVYTQYFD ISYIPSTVFF FNGQHMKVDY GSPDHTKFVG SFKTKQDFID LIEVIYRGAM RGKLIVQSPI DPKNIPKYDL LYQDI|
|Purity||> 90% pure|
|Molecular Weight||21.1 kDa (185aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, 30% glycerol and 100mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||TXNL4B, also known as Dim2 or DLP, belongs to the DIM1 family that plays an essential role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interacts with the PRPF6 subunit of the spliceosome. Recombinant human TXNL4B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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