UBE2R2 protein (His tag) (80R-3507)
Purified recombinant UBE2R2 protein (His tag)
|Synonyms||CDC34B protein, E2-CDC34B protein, UBC3B protein, UBE 2R2 protein, UBE-2R2 protein|
Coomassie blue stained SDS-PAGE of UBE2R2 protein (His tag) (80R-3507)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-238 aa: MGSSHHHHHH SSGLVPRGSH MGSMAQQQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPIDYPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S|
|Purity||> 85% pure|
|Method of Purification||UBE2R2 protein was purified by using conventional chromatography techniques|
|Molecular Weight||29.6 kDa|
|Form & Buffer||Supplied in liquid form in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||UBE2R2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This protein is a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.|
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