UBP1 antibody (10R-1503)

Mouse monoclonal UBP1 antibody

Synonyms Monoclonal UBP1 antibody, Anti-UBP1 antibody, UBP-1 antibody, LBP1A antibody, LBP1B antibody, UBP-1, LBP-1a antibody, UBP1, UBP 1, DKFZp686L1745 antibody, UBP 1 antibody, Upstream-binding protein 1 antibody, LBP-1B antibody
Specificity Human UBP1
Cross Reactivity Human. Other species not studied
Applications Dot Blot, ICC, WB
Immunogen UBP1 antibody was raised in mouse using recombinant Human Upstream Binding Protein 1 (Lbp-1A)

Images

Immunofluorescent staining using UBP1 antibody (10R-1503)

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-UBP1 antibody.

Specifications

Host Mouse
Clone 327C1a
Isotype IgG1
Method of Purification UBP1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer UBP1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml, ICC: 2-100 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 . Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 . Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

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Images

  • Immunofluorescent staining using UBP1 antibody (10R-1503) | Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-UBP1 antibody.
  • Western Blot analysis of immunized recombinant protein using UBP1 antibody (10R-1503) | Left: UBP1 staining. Right: Coomassie Blue staining of immunized recombinant protein.

Availability: In stock

Price: $190.00
Size: 50 ug
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