UCK2 protein (His tag) (80R-1565)
Purified recombinant Human UCK2 protein
|Synonyms||UCK-2, UMPK, UCK 2, UCK 2 protein, UCK2, UCK-2 protein, UK protein, TSA903 protein, Uridine-cytidine kinase 2 protein|
Coomassie Blue stained SDS-PAGE of UCK2 protein (His tag) (80R-1565)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-261 amino acids: MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQKQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRLSRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK RQASESSSRP HLEHHHHHH|
|Purity||> 90% pure|
|Molecular Weight||30.3 kDa (269aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF and 1mM EDTA.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||UCK2 also known as uridine-cytidine kinase 2 is belongs to the uridinekinase family. UCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. It plays a role in the production of pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B. Recombinant human UCK2 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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