UFD1L protein (His tag) (80R-2947)

Purified recombinant THAP3 protein (His tag)

Synonyms Ubiquitin fusion degradation protein 1 homolog isoform A protein, UFD1 protein, UFD 1L protein, UFD-1L protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of UFD1L protein (His Tag) (80R-2947)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-307 aa: MGSSHHHHHH SSGLVPRGSH MGSMFSFNMF DHPIPRVFQN RFSTQYRCFS VSMLAGPNDR SDVEKGGKII MPPSALDQLS RLNITYPMLF KLTNKNSDRM THCGVLEFVA DEGICYLPHW MMQNLLLEEG GLVQVESVNL QVATYSKFQP QSPDFLDITN PKAVLENALR NFACLTTGDV IAINYNEKIY ELRVMETKPD KAVSIIECDM NVDFDAPLGY KEPERQVQHE ESTEGEADHS GYAGELGFRA FSGSGNRLDG KKKGVEPSPS PIKPGDIKRG IPNYEFKLGK ITFIRNSRPL VKKVEEDEAG GRFVAFSGEG QSLRKKGRKP
Expression System E.coli
Purity > 85% pure
Molecular Weight 36.9 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% glycerol, 1mM DTT
Concentration 250 ug/ml

Storage & Safety

Storage Store at 4 deg C for up to 2 weeks. For long term storage, aliquot and store at -20 deg C to -70 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance UFD1L forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • SDS-PAGE analysis of UFD1L protein (His Tag) (80R-2947) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $375.00
Size: 50 ug
OR
Shipping
View Our Distributors