VDAC1 antibody (20R-2949)

Rabbit polyclonal VDAC1 antibody

Synonyms Polyclonal VDAC1 antibody, Anti-VDAC1 antibody, VDAC1 antibody, voltage-dependent anion channel 1 antibody, AL033343 antibody, BOS_8120 antibody, BR1-VDAC antibody, brain-derived voltage-dependent anion channel 1 antibody, fa13f11 antibody, mVDAC1 antibody, mVDAC5 antibody, outer mitochondrial membrane protein porin 1 antibody, plasmalemmal porin antibody, PORIN antibody, porin 31HL antibody, porin 31HM antibody, RP23-289H16.1 antibody, rVDAC1 antibody, VDAC-1 antibody, Vdac5 antibody, VDAC-5 antibody, voltage-dependent anion-selective channel protein 1 antibody, voltage-dependent anion-selective channel protein 1-like antibody, voltage-dependent anion-selective channel protein 5 antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen VDAC1 antibody was raised in Rabbit using Synthesis peptide (KLH coupled) corresponding to C-terminal residues of Human VDAC1 as the immunogen

Images

Western Blot analysis using VDAC1 antibody (20R-2949)

Specifications

Host Rabbit
Isotype IgG
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC contitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.

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Images

  • Western Blot analysis using VDAC1 antibody (20R-2949) |

Availability: In stock

Price: $295.00
Size: 100 ul
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