VDR antibody (10R-1504)

Mouse monoclonal VDR antibody

Synonyms Monoclonal VDR antibody, Anti-VDR antibody, NR1I1 antibody, Anti VDR antibody, NR1I1 antibody, Vitamin D3 receptor antibody, VDR antibody, Vitamin D3 receptor antibody
Specificity Human VDR
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen VDR antibody was raised in mouse using recombinant Human Vitamin D (1,25-Dihydroxyvitamin D3) Receptor

Images

Western Blot analysis of immunized recombinant protein using VDR antibody (10R-1504)

Specifications

Host Mouse
Clone 333C6a
Isotype IgG1
Method of Purification VDR antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer VDR antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets.

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Images

  • Western Blot analysis of immunized recombinant protein using VDR antibody (10R-1504)

Availability: In stock

Price: $190.00
Size: 50 ug
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