Visininlike protein1 protein (30R-1384)

Purified recombinant Human Visininlike protein1 protein

Synonyms Neurocalcin alpha protein, Visinin.Visinin like 1 protein, HLP3 protein, NVL1 protein, Visininlike 1, HLP 3 protein, Visinin like protein 1.VISL 1., NVL 1 protein, VILIP-1 protein, VILIP protein, VILIP protein, HPCAL 3 protein, Visininlike -1 protein, Visininlike -1, Visininlike 1, VSNL1 protein, Visininlike 1 protein, Hippocalcin like protein 3 protein, HUVISL1 protein, VLP-1 protein, HPCAL3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of Visininlike protein1 protein (30R-1384)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-191 amino acids: MGKQNSKLAP EVMEDLVKST EFNEHELKQW YKGFLKDCPS GRLNLEEFQQ LYVKFFPYGD ASKFAQHAFR TFDKNGDGTI DFREFICALS ITSRGSFEQK LNWAFNMYDL DGDGKITRVE MLEIIEAIYK MVGTVIMMKM NEDGLTPEQR VDKIFSKMDK NKDDQITLDE FKEAAKSDPS IVLLLQCDIQ K
Expression System E.coli
Purity > 95% pure
Molecular Weight 22.1 kDa (191aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 1mM DTT, and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E. coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of Visininlike protein1 protein (30R-1384) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $180.00
Size: 100 ug
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