Vitamin D binding protein antibody (10R-8430)

Mouse monoclonal Vitamin D binding protein antibody

Synonyms Monoclonal Vitamin D binding protein antibody, Anti-Vitamin D binding protein antibody, GC antibody, group-specific component (vitamin D binding protein) antibody, CG13927-PA antibody, CG13927-PB antibody, dbp antibody, DBP02 antibody, dbp/gc antibody, DgammaC antibody, dGC antibody, Dmel_CG13927 antibody, EGK_15808 antibody, gammaC antibody, gamma-glutamyl carboxylase antibody, gamma-glutamyl-carboxylase antibody, gc-globulin antibody, GC-PA antibody, GC-PB antibody, GRD3 antibody, group specific component antibody, Group-specific component (vitamin D-binding protein) antibody, RATDBP02 antibody, VDB antibody, vdbg antibody, vdbp antibody, vitamin D-binding alpha-globulin antibody, vitamin D binding protein antibody, vitamin D-binding protein antibody, vitamin-D binding protein antibody, VTDB antibody
Cross Reactivity Human
Applications IHC-P, WB
Immunogen Vitamin D binding protein antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

Images

Western Blot analysis using Vitamin D binding protein antibody (10R-8430)

Specifications

Host Mouse
Clone 2B12
Isotype IgG2b kappa
Method of Purification Vitamin D binding protein antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000, IHC-P

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Vitamin D-binding protein (DBP, VDBP), also called group-specific component (Gc) and macrophage-activating factor (GcMAF/DBP-MAF), is 52 to 58 kDa plasma glycoprotein with many functions, such as transport of vitamin D metabolites, control of bone development, binding of fatty acids, sequestration of actin, and modulating immune and inflammatory responses. DBP is synthesized predominantly by hepatic parenchymal cells and detected in plasma, cerebrospinal fluid, seminal fluid, saliva and breast milk. The exploitation of the unique properties of DBP could enable the development of important therapeutic agents such as vitamin D-associated conditions, actin sequestering in trauma and inflammation, chronic obstructive pulmonary disease, osteopetrosis, cancer therapy and immune modulation by macrophage activation. The DBP molecule is therefore an ideal candidate molecule for further investigation by biotechnology-based companies seeking a platform from which to pursue new therapeutic options.

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Images

  • Western Blot analysis using Vitamin D binding protein antibody (10R-8430) |

Availability: In stock

Price: $295.00
Size: 100 ul
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