VTCN1 protein (His tag) (80R-3611)
Purified recombinant VTCN1 protein (His tag)
|Synonyms||B7-H4 protein, B7h.5 protein, B7H4 protein, B7S1 protein, B7X protein, PRO1291 protein, RP11-229A19.4 protein, VCTN 1 protein, VCTN-1 protein|
Coomassie blue stained SDS-PAGE of VTCN1 protein (His tag) (80R-3611)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||25-259 aa: MGSSHHHHHH SSGLVPRGSH MGSLIIGFGI SGRHSITVTT VASAGNIGED GILSCTFEPD IKLSDIVIQW LKEGVLGLVH EFKEGKDELS EQDEMFRGRT AVFADQVIVG NASLRLKNVQ LTDAGTYKCY IITSKGKGNA NLEYKTGAFS MPEVNVDYNA SSETLRCEAP RWFPQPTVVW ASQVDQGANF SEVSNTSFEL NSENVTMKVV SVLYNVTINN TYSCMIENDI AKATGDIKVT ESEIKRRSHL QLLNSKAS|
|Purity||> 90% pure|
|Method of Purification||VTCN1 protein was purified by using conventional chromatography techniques|
|Molecular Weight||28.2 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol|
Storage & Safety
|Storage||Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.|
|Biological Significance||The VCTN1 is a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.|
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