WDR5 antibody (10R-2213)
Mouse monoclonal WDR5 antibody
|Synonyms||Monoclonal WDR5 antibody, Anti-WDR5 antibody, BIG-3 antibody, WDR-5 antibody, WD repeat-containing protein 5 antibody, WDR-5, BIG 3 antibody, SWD3 antibody, WDR 5, WDR 5 antibody, WDR5, WDR-5 antibody, WDR 5 antibody|
|Immunogen||WDR5 antibody was raised in Mouse using a purified recombinant fragment of human WDR5 expressed in E. coli as the immunogen.|
Western Blot analysis using WDR5 antibody (10R-2213)
Western Blot showing WDR5 antibody used against Hela (1) cell lysate.
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:200-1:1000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||WDR5, also designated BMP-2-induced gene 3 kb or BIG-3, belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. This protein is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. WDR5 may play a role in its function of accelerating osteoblast differentiation. Recombinant human WDR5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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