XRCC6 antibody (10R-1402)

Mouse monoclonal XRCC6 antibody

Synonyms Monoclonal XRCC6 antibody, Anti-XRCC6 antibody, XRCC-6, TLAA antibody, XRCC-6 antibody, ML8 antibody, XRCC 6, XRCC 6 antibody, CTC75 antibody, XRCC6, -ray repair complementing defective repair in Chinese hamster cells 6 antibody, KU70 antibody, CTCBF antibody
Specificity Human XRCC6
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen XRCC6 antibody was raised in mouse using recombinant Human X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 6 (Ku Autoantigen, 70Kda)

Images

Western Blot analysis of immunized recombinant protein using XRCC6 antibody (10R-1402)

Specifications

Host Mouse
Clone 995C1b
Isotype IgG1
Method of Purification XRCC6 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer XRCC6 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

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Images

  • Western Blot analysis of immunized recombinant protein using XRCC6 antibody (10R-1402)

Availability: In stock

Price: $190.00
Size: 50 ug
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