YWHAQ antibody (70R-10463)

Affinity purified rabbit polyclonal YWHAQ antibody

Synonyms Polyclonal YWHAQ antibody, Anti-YWHAQ antibody, 1C5 antibody, theta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, HS1 antibody
Cross Reactivity Human, Mouse, Rat, Dog, Rabbit, African Clawed Frog, Bovine, Chicken, Zebrafish
Applications IHC, WB
Immunogen YWHAQ antibody was raised in rabbit using the N terminal of YWHAQ as the immunogen
Assay Information YWHAQ Blocking Peptide, catalog no. 33R-8902, is also available for use as a blocking control in assays to test for specificity of this YWHAQ antibody

Images

Immunohistochemical staining using YWHAQ antibody (70R-10463)

YWHAQ antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

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Images

  • Immunohistochemical staining using YWHAQ antibody (70R-10463) | YWHAQ antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X.
  • Western Blot analysis using YWHAQ antibody (70R-10463) | YWHAQ antibody (70R-10463) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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