ZAP70 antibody (10R-1958)

Mouse monoclonal ZAP70 antibody

Synonyms Monoclonal ZAP70 antibody, Anti-ZAP70 antibody, Zeta-chain associated protein kinase antibody, Zeta-chain associated protein kinase 70 antibody, ZAP70, ZAP 70, ZAP-70, ZAP 70 antibody, ZAP-70 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen ZAP70 antibody was raised in Mouse using a purified recombinant fragment of human ZAP70 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using ZAP70 antibody (10R-1958)

Immunohistochemical analysis of paraffin-embedded human lymph tumor, showing cytoplasmic localization using ZAP70 antibody with DAB staining

Specifications

Host Mouse
Clone 3D2A4
Isotype IgG1
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance ZAP70 is a member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. ZAP70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene. ZAP70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunohistochemical staining using ZAP70 antibody (10R-1958) | Immunohistochemical analysis of paraffin-embedded human lymph tumor, showing cytoplasmic localization using ZAP70 antibody with DAB staining
  • Western Blot analysis using ZAP70 antibody (10R-1958) | Western Blot showing ZAP70 antibody used against Jurkat cell lysate (1).

Availability: In stock

Price: $395.00
Size: 100 ul
OR
Shipping
View Our Distributors